Entity Details

Primary name ELNE_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UP87
EntryNameELNE_MOUSE
FullNameNeutrophil elastase
TaxID10090
Evidenceevidence at protein level
Length265
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesElane

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001878 response to yeast
GO:0002020 protease binding
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0002523 leukocyte migration involved in inflammatory response
GO:0002812 biosynthetic process of antibacterial peptides active against Gram-negative bacteria
GO:0003714 transcription corepressor activity
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006508 proteolysis
GO:0006909 phagocytosis
GO:0008201 heparin binding
GO:0008233 peptidase activity
GO:0009411 response to UV
GO:0009986 cell surface
GO:0017053 transcription repressor complex
GO:0019955 cytokine binding
GO:0030141 secretory granule
GO:0032496 response to lipopolysaccharide
GO:0032682 negative regulation of chemokine production
GO:0032717 negative regulation of interleukin-8 production
GO:0032757 positive regulation of interleukin-8 production
GO:0042742 defense response to bacterium
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050778 positive regulation of immune response
GO:0050832 defense response to fungus
GO:0050900 leukocyte migration
GO:0062023 collagen-containing extracellular matrix
GO:0070945 neutrophil-mediated killing of gram-negative bacterium
GO:0070947 neutrophil-mediated killing of fungus
GO:1903238 positive regulation of leukocyte tethering or rolling

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ELNE_MOUSEA1AT1_MOUSEBioGRID11961105 details