Entity Details

Primary name ZCCHV_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UPF5
EntryNameZCCHV_MOUSE
FullNameZinc finger CCCH-type antiviral protein 1
TaxID10090
Evidenceevidence at protein level
Length946
SequenceStatuscomplete
DateCreated2008-04-29
DateModified2021-06-02

Ontological Relatives

GenesZc3hav1

GO terms

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GOName
GO:0003723 RNA binding
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006471 protein ADP-ribosylation
GO:0009615 response to virus
GO:0017151 DEAD/H-box RNA helicase binding
GO:0032481 positive regulation of type I interferon production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032781 positive regulation of ATPase activity
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045071 negative regulation of viral genome replication
GO:0045087 innate immune response
GO:0046872 metal ion binding
GO:0050691 regulation of defense response to virus by host
GO:0051607 defense response to virus
GO:0061014 positive regulation of mRNA catabolic process
GO:0071360 cellular response to exogenous dsRNA
GO:0098586 cellular response to virus
GO:1900246 positive regulation of RIG-I signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000571 Zinc finger, CCCH-typeDomainDomain
IPR004170 WWE domainDomainDomain
IPR012317 Poly(ADP-ribose) polymerase, catalytic domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037197 WWE domain superfamilyFamilyHomologous superfamily
IPR040954 ZAP, zinc fingerDomainDomain
IPR041360 ZAP, helix turn helix N-terminal domainDomainDomain

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink