Entity Details

Primary name IQGA2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UQ44
EntryNameIQGA2_MOUSE
FullNameRas GTPase-activating-like protein IQGAP2
TaxID10090
Evidenceevidence at protein level
Length1575
SequenceStatuscomplete
DateCreated2008-11-25
DateModified2021-06-02

Ontological Relatives

GenesIqgap2

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005516 calmodulin binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005902 microvillus
GO:0009986 cell surface
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0031267 small GTPase binding
GO:0032956 regulation of actin cytoskeleton organization
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0051015 actin filament binding
GO:0070493 thrombin-activated receptor signaling pathway
GO:0071933 Arp2/3 complex binding
GO:2000249 regulation of actin cytoskeleton reorganization

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR000593 RasGAP protein, C-terminalDomainDomain
IPR001202 WW domainDomainDomain
IPR001715 Calponin homology domainDomainDomain
IPR001936 Ras GTPase-activating domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR023152 Ras GTPase-activating protein, conserved siteSiteConserved site
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink