Entity Details

Primary name TTBK2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UVR3
EntryNameTTBK2_MOUSE
FullNameTau-tubulin kinase 2
TaxID10090
Evidenceevidence at protein level
Length1243
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesTtbk2

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005829 cytosol
GO:0007026 negative regulation of microtubule depolymerization
GO:0007224 smoothened signaling pathway
GO:0008589 regulation of smoothened signaling pathway
GO:0018105 peptidyl-serine phosphorylation
GO:0019894 kinesin binding
GO:0021549 cerebellum development
GO:0021681 cerebellar granular layer development
GO:0021915 neural tube development
GO:0021935 cerebellar granule cell precursor tangential migration
GO:0030334 regulation of cell migration
GO:0030900 forebrain development
GO:0035869 ciliary transition zone
GO:0036064 ciliary basal body
GO:0042733 embryonic digit morphogenesis
GO:0060271 cilium assembly
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902817 negative regulation of protein localization to microtubule
GO:1902857 positive regulation of non-motile cilium assembly
GO:1903828 negative regulation of cellular protein localization
GO:1904527 negative regulation of microtubule binding
GO:1990403 embryonic brain development

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Interactions

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