Entity Details

Primary name ARBK2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UYH7
EntryNameARBK2_MOUSE
FullNameBeta-adrenergic receptor kinase 2
TaxID10090
Evidenceevidence at protein level
Length688
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesGrk3

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0004703 G protein-coupled receptor kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005929 cilium
GO:0006468 protein phosphorylation
GO:0006886 intracellular protein transport
GO:0007165 signal transduction
GO:0016020 membrane
GO:0030018 Z disc
GO:0030424 axon
GO:0031623 receptor internalization
GO:0031748 D1 dopamine receptor binding
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
GO:0043647 inositol phosphate metabolic process
GO:0044292 dendrite terminus
GO:0045121 membrane raft
GO:0045202 synapse
GO:0046154 rhodopsin metabolic process
GO:0047696 beta-adrenergic receptor kinase activity
GO:0048471 perinuclear region of cytoplasm
GO:0097225 sperm midpiece

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000239 GPCR kinaseFamilyFamily
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016137 RGS domainDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036305 RGS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ARBK2_MOUSEOPN4_MOUSEIntAct22159583 details