Entity Details

Primary name SHAN3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ4ACU6
EntryNameSHAN3_MOUSE
FullNameSH3 and multiple ankyrin repeat domains protein 3
TaxID10090
Evidenceevidence at protein level
Length1730
SequenceStatuscomplete
DateCreated2007-06-12
DateModified2021-06-02

Ontological Relatives

GenesShank3

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001838 embryonic epithelial tube formation
GO:0003779 actin binding
GO:0005737 cytoplasm
GO:0007416 synapse assembly
GO:0007611 learning or memory
GO:0007612 learning
GO:0007613 memory
GO:0007626 locomotory behavior
GO:0008022 protein C-terminus binding
GO:0008270 zinc ion binding
GO:0014069 postsynaptic density
GO:0017124 SH3 domain binding
GO:0021773 striatal medium spiny neuron differentiation
GO:0030160 synaptic receptor adaptor activity
GO:0030534 adult behavior
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0032232 negative regulation of actin filament bundle assembly
GO:0035176 social behavior
GO:0035255 ionotropic glutamate receptor binding
GO:0035640 exploration behavior
GO:0035641 locomotory exploration behavior
GO:0040011 locomotion
GO:0042297 vocal learning
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043197 dendritic spine
GO:0043621 protein self-association
GO:0044309 neuron spine
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045794 negative regulation of cell volume
GO:0048167 regulation of synaptic plasticity
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0048854 brain morphogenesis
GO:0050807 regulation of synapse organization
GO:0050885 neuromuscular process controlling balance
GO:0051124 synaptic assembly at neuromuscular junction
GO:0051835 positive regulation of synapse structural plasticity
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060076 excitatory synapse
GO:0060170 ciliary membrane
GO:0060291 long-term synaptic potentiation
GO:0060292 long-term synaptic depression
GO:0060997 dendritic spine morphogenesis
GO:0060999 positive regulation of dendritic spine development
GO:0061001 regulation of dendritic spine morphogenesis
GO:0071625 vocalization behavior
GO:0097107 postsynaptic density assembly
GO:0097110 scaffold protein binding
GO:0097113 AMPA glutamate receptor clustering
GO:0097114 NMDA glutamate receptor clustering
GO:0097117 guanylate kinase-associated protein clustering
GO:0098919 structural constituent of postsynaptic density
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:1900271 regulation of long-term synaptic potentiation
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1900451 positive regulation of glutamate receptor signaling pathway
GO:1900452 regulation of long-term synaptic depression
GO:1904717 regulation of AMPA glutamate receptor clustering
GO:2000311 regulation of AMPA receptor activity
GO:2000463 positive regulation of excitatory postsynaptic potential
GO:2000821 regulation of grooming behavior
GO:2000822 regulation of behavioral fear response
GO:2000969 positive regulation of AMPA receptor activity

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR001660 Sterile alpha motif domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR041489 PDZ domain 6DomainDomain

Diseases

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