Entity Details

Primary name TET2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ4JK59
EntryNameTET2_MOUSE
FullNameMethylcytosine dioxygenase TET2
TaxID10090
Evidenceevidence at protein level
Length1912
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesTet2

GO terms

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GOName
GO:0001822 kidney development
GO:0002318 myeloid progenitor cell differentiation
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006211 5-methylcytosine catabolic process
GO:0006493 protein O-linked glycosylation
GO:0007049 cell cycle
GO:0008198 ferrous iron binding
GO:0008270 zinc ion binding
GO:0009791 post-embryonic development
GO:0019857 5-methylcytosine metabolic process
GO:0019858 cytosine metabolic process
GO:0020027 hemoglobin metabolic process
GO:0030097 hemopoiesis
GO:0030099 myeloid cell differentiation
GO:0035511 oxidative DNA demethylation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048536 spleen development
GO:0048872 homeostasis of number of cells
GO:0061484 hematopoietic stem cell homeostasis
GO:0070579 methylcytosine dioxygenase activity
GO:0070989 oxidative demethylation
GO:0072576 liver morphogenesis
GO:0080111 DNA demethylation
GO:0080182 histone H3-K4 trimethylation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR024779 2OGFeDO, oxygenase domainDomainDomain
IPR040175 Methylcytosine dioxygenase TET1/2/3FamilyFamily

Diseases

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