Entity Details

Primary name ECE1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ4PZA2
EntryNameECE1_MOUSE
FullNameEndothelin-converting enzyme 1
TaxID10090
Evidenceevidence at protein level
Length769
SequenceStatuscomplete
DateCreated2006-06-27
DateModified2021-06-02

Ontological Relatives

GenesEce1

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001921 positive regulation of receptor recycling
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005768 endosome
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0007507 heart development
GO:0008217 regulation of blood pressure
GO:0008270 zinc ion binding
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010814 substance P catabolic process
GO:0010815 bradykinin catabolic process
GO:0010816 calcitonin catabolic process
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0016486 peptide hormone processing
GO:0030141 secretory granule
GO:0031410 cytoplasmic vesicle
GO:0031982 vesicle
GO:0033093 Weibel-Palade body
GO:0034959 endothelin maturation
GO:0042447 hormone catabolic process
GO:0042733 embryonic digit morphogenesis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043583 ear development
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0060037 pharyngeal system development
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0097746 blood vessel diameter maintenance

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000718 Peptidase M13FamilyFamily
IPR008753 Peptidase M13, N-terminal domainDomainDomain
IPR018497 Peptidase M13, C-terminal domainDomainDomain
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR029734 Endothelin-converting enzyme 1FamilyFamily
IPR042089 Peptidase M13, domain 2FamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink