Entity Details

Primary name HERC2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ4U2R1
EntryNameHERC2_MOUSE
FullNameE3 ubiquitin-protein ligase HERC2
TaxID10090
Evidenceevidence at protein level
Length4836
SequenceStatuscomplete
DateCreated2006-04-04
DateModified2021-06-02

Ontological Relatives

GenesHerc2

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005743 mitochondrial inner membrane
GO:0005814 centriole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0008270 zinc ion binding
GO:0016567 protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0032183 SUMO binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000408 Regulator of chromosome condensation, RCC1RepeatRepeat
IPR000433 Zinc finger, ZZ-typeDomainDomain
IPR000569 HECT domainDomainDomain
IPR001199 Cytochrome b5-like heme/steroid binding domainDomainDomain
IPR004939 APC10/DOC domainDomainDomain
IPR006624 Beta-propeller repeat TECPRRepeatRepeat
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein IIFamilyHomologous superfamily
IPR010606 Mib-herc2DomainDomain
IPR014722 Ribosomal protein L2, domain 2FamilyHomologous superfamily
IPR021097 CPH domainDomainDomain
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR036400 Cytochrome b5-like heme/steroid binding domain superfamilyFamilyHomologous superfamily
IPR037252 Mib/herc2 domain superfamilyFamilyHomologous superfamily
IPR037976 HERC2, APC10 domainDomainDomain
IPR041987 HERC2, zinc finger, ZZ-typeDomainDomain
IPR043145 Zinc finger, ZZ-type superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions