Entity Details

Primary name RC3H1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ4VGL6
EntryNameRC3H1_MOUSE
FullNameRoquin-1
TaxID10090
Evidenceevidence at protein level
Length1130
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesRc3h1

GO terms

Show/Hide Table
GOName
GO:0000209 protein polyubiquitination
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000932 P-body
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0001782 B cell homeostasis
GO:0002634 regulation of germinal center formation
GO:0002635 negative regulation of germinal center formation
GO:0003725 double-stranded RNA binding
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005737 cytoplasm
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008270 zinc ion binding
GO:0010468 regulation of gene expression
GO:0010494 cytoplasmic stress granule
GO:0010608 posttranscriptional regulation of gene expression
GO:0030889 negative regulation of B cell proliferation
GO:0033962 P-body assembly
GO:0035198 miRNA binding
GO:0035613 RNA stem-loop binding
GO:0042098 T cell proliferation
GO:0043029 T cell homeostasis
GO:0043488 regulation of mRNA stability
GO:0045623 negative regulation of T-helper cell differentiation
GO:0046007 negative regulation of activated T cell proliferation
GO:0048535 lymph node development
GO:0048536 spleen development
GO:0050852 T cell receptor signaling pathway
GO:0050856 regulation of T cell receptor signaling pathway
GO:0061014 positive regulation of mRNA catabolic process
GO:0061158 3'-UTR-mediated mRNA destabilization
GO:0061470 T follicular helper cell differentiation
GO:0061630 ubiquitin protein ligase activity
GO:0071347 cellular response to interleukin-1
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000320 negative regulation of T-helper 17 cell differentiation
GO:2000628 regulation of miRNA metabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Cytoplasmic granule

Domains

Show/Hide Table
DomainNameCategoryType
IPR000571 Zinc finger, CCCH-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR027370 RING-type zinc-finger, LisH dimerisation motifDomainDomain
IPR032671 Roquin-1FamilyFamily
IPR036855 Zinc finger, CCCH-type superfamilyFamilyHomologous superfamily
IPR041523 Roquin IIDomainDomain

Diseases

Show/Hide Table