Entity Details

Primary name BRE1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ5DTM8
EntryNameBRE1A_MOUSE
FullNameE3 ubiquitin-protein ligase BRE1A
TaxID10090
Evidenceevidence at protein level
Length973
SequenceStatuscomplete
DateCreated2005-12-20
DateModified2021-06-02

Ontological Relatives

GenesRnf20

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0002039 p53 binding
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003730 mRNA 3'-UTR binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006355 regulation of transcription, DNA-templated
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010390 histone monoubiquitination
GO:0016574 histone ubiquitination
GO:0030336 negative regulation of cell migration
GO:0031062 positive regulation of histone methylation
GO:0031625 ubiquitin protein ligase binding
GO:0033503 HULC complex
GO:0033523 histone H2B ubiquitination
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:1900364 negative regulation of mRNA polyadenylation
GO:2001168 positive regulation of histone H2B ubiquitination

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013956 E3 ubiquitin ligase Bre1FamilyFamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site

Diseases

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