Entity Details

Primary name FA2H_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ5MPP0
EntryNameFA2H_MOUSE
FullNameFatty acid 2-hydroxylase
TaxID10090
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated2007-12-04
DateModified2021-06-02

Ontological Relatives

GenesFa2h

GO terms

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GOName
GO:0001949 sebaceous gland cell differentiation
GO:0005506 iron ion binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006631 fatty acid metabolic process
GO:0006633 fatty acid biosynthetic process
GO:0006679 glucosylceramide biosynthetic process
GO:0006682 galactosylceramide biosynthetic process
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0020037 heme binding
GO:0030258 lipid modification
GO:0032286 central nervous system myelin maintenance
GO:0032287 peripheral nervous system myelin maintenance
GO:0042127 regulation of cell population proliferation
GO:0042634 regulation of hair cycle
GO:0044857 plasma membrane raft organization
GO:0046513 ceramide biosynthetic process
GO:0061436 establishment of skin barrier
GO:0080132 fatty acid alpha-hydroxylase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001199 Cytochrome b5-like heme/steroid binding domainDomainDomain
IPR006694 Fatty acid hydroxylaseDomainDomain
IPR014430 Sterol desaturase Scs7FamilyFamily
IPR018506 Cytochrome b5, heme-binding siteSiteBinding site
IPR036400 Cytochrome b5-like heme/steroid binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink