Entity Details

Primary name ABR_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ5SSL4
EntryNameABR_MOUSE
FullNameActive breakpoint cluster region-related protein
TaxID10090
Evidenceevidence at protein level
Length859
SequenceStatuscomplete
DateCreated2008-11-25
DateModified2021-06-02

Ontological Relatives

GenesAbr

GO terms

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GOName
GO:0002692 negative regulation of cellular extravasation
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007420 brain development
GO:0016020 membrane
GO:0030036 actin cytoskeleton organization
GO:0030336 negative regulation of cell migration
GO:0030424 axon
GO:0032496 response to lipopolysaccharide
GO:0035556 intracellular signal transduction
GO:0042472 inner ear morphogenesis
GO:0043114 regulation of vascular permeability
GO:0043197 dendritic spine
GO:0043314 negative regulation of neutrophil degranulation
GO:0050728 negative regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
GO:0050804 modulation of chemical synaptic transmission
GO:0050885 neuromuscular process controlling balance
GO:0060313 negative regulation of blood vessel remodeling
GO:0090630 activation of GTPase activity
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component

Subcellular Location

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Subcellular Location
Cell junction
Cell projection

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001849 Pleckstrin homology domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR037769 Abr/BcrFamilyFamily
IPR037865 Active breakpoint cluster region-related protein, PH domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ABR_MOUSERAC1_HUMANBioGRID32203420 details
ABR_MOUSERAC1_MOUSEBioGRID17116687 details