Entity Details

Primary name FANCJ_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ5SXJ3
EntryNameFANCJ_MOUSE
FullNameFanconi anemia group J protein homolog
TaxID10090
Evidenceevidence at transcript level
Length1174
SequenceStatuscomplete
DateCreated2005-10-25
DateModified2021-06-02

Ontological Relatives

GenesBrip1

GO terms

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GOName
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006289 nucleotide-excision repair
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007129 homologous chromosome pairing at meiosis
GO:0007283 spermatogenesis
GO:0007284 spermatogonial cell division
GO:0007286 spermatid development
GO:0008285 negative regulation of cell population proliferation
GO:0008584 male gonad development
GO:0009636 response to toxic substance
GO:0010629 negative regulation of gene expression
GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination
GO:0031965 nuclear membrane
GO:0046872 metal ion binding
GO:0051026 chiasma assembly
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0071295 cellular response to vitamin
GO:0071456 cellular response to hypoxia
GO:0072520 seminiferous tubule development
GO:1904385 cellular response to angiotensin
GO:1990918 double-strand break repair involved in meiotic recombination

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR006554 Helicase-like, DEXD box c2 typeDomainDomain
IPR006555 ATP-dependent helicase, C-terminalDomainDomain
IPR010614 DEAD2DomainDomain
IPR013020 ATP-dependent helicase Rad3/Chl1-likeFamilyFamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014013 Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-typeDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
FANCJ_MOUSETLX3_MOUSEBioGRID, IntAct20211142 details