Entity Details

Primary name PDE8B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionE9Q4S1
EntryNamePDE8B_MOUSE
FullNameHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
TaxID10090
Evidenceevidence at protein level
Length865
SequenceStatuscomplete
DateCreated2011-12-14
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0001662 behavioral fear response
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0006198 cAMP catabolic process
GO:0007165 signal transduction
GO:0008542 visual learning
GO:0035106 operant conditioning
GO:0046676 negative regulation of insulin secretion
GO:0046872 metal ion binding
GO:0050885 neuromuscular process controlling balance
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0090032 negative regulation of steroid hormone biosynthetic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domainDomainDomain
IPR003607 HD/PDEase domainDomainDomain
IPR013938 3'5'-cyclic nucleotide phosphodiesterase PDE8DomainDomain
IPR023088 3'5'-cyclic nucleotide phosphodiesteraseFamilyFamily
IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved siteSiteConserved site
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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