Entity Details

Primary name NFAC2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60591
EntryNameNFAC2_MOUSE
FullNameNuclear factor of activated T-cells, cytoplasmic 2
TaxID10090
Evidenceevidence at protein level
Length927
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesNfatc2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006974 cellular response to DNA damage stimulus
GO:0008134 transcription factor binding
GO:0010628 positive regulation of gene expression
GO:0014904 myotube cell development
GO:0016477 cell migration
GO:0019902 phosphatase binding
GO:0030890 positive regulation of B cell proliferation
GO:0033173 calcineurin-NFAT signaling cascade
GO:0042493 response to drug
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050853 B cell receptor signaling pathway
GO:1901741 positive regulation of myoblast fusion
GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002909 IPT domainDomainDomain
IPR008366 Nuclear factor of activated T cells (NFAT)FamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR011539 Rel homology domain (RHD), DNA-binding domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR032397 Rel homology dimerisation domainDomainDomain
IPR037059 Rel homology domain (RHD), DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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