Entity Details

Primary name AA2AR_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60613
EntryNameAA2AR_MOUSE
FullNameAdenosine receptor A2a
TaxID10090
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesAdora2a

GO terms

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GOName
GO:0001609 G protein-coupled adenosine receptor activity
GO:0001963 synaptic transmission, dopaminergic
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0001975 response to amphetamine
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006469 negative regulation of protein kinase activity
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007271 synaptic transmission, cholinergic
GO:0007626 locomotory behavior
GO:0008285 negative regulation of cell population proliferation
GO:0012505 endomembrane system
GO:0014049 positive regulation of glutamate secretion
GO:0014057 positive regulation of acetylcholine secretion, neurotransmission
GO:0014061 regulation of norepinephrine secretion
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0019899 enzyme binding
GO:0030424 axon
GO:0030425 dendrite
GO:0030673 axolemma
GO:0031000 response to caffeine
GO:0031802 type 5 metabotropic glutamate receptor binding
GO:0032230 positive regulation of synaptic transmission, GABAergic
GO:0032279 asymmetric synapse
GO:0035249 synaptic transmission, glutamatergic
GO:0035810 positive regulation of urine volume
GO:0035815 positive regulation of renal sodium excretion
GO:0040013 negative regulation of locomotion
GO:0042311 vasodilation
GO:0042493 response to drug
GO:0042734 presynaptic membrane
GO:0042755 eating behavior
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043116 negative regulation of vascular permeability
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043279 response to alkaloid
GO:0043524 negative regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0045211 postsynaptic membrane
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep
GO:0046636 negative regulation of alpha-beta T cell activation
GO:0048143 astrocyte activation
GO:0048786 presynaptic active zone
GO:0048812 neuron projection morphogenesis
GO:0050714 positive regulation of protein secretion
GO:0050728 negative regulation of inflammatory response
GO:0051393 alpha-actinin binding
GO:0051881 regulation of mitochondrial membrane potential
GO:0051899 membrane depolarization
GO:0051924 regulation of calcium ion transport
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060079 excitatory postsynaptic potential
GO:0060080 inhibitory postsynaptic potential
GO:0060134 prepulse inhibition
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:1900273 positive regulation of long-term synaptic potentiation
GO:2000300 regulation of synaptic vesicle exocytosis
GO:2001235 positive regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001513 Adenosine A2A receptorFamilyFamily
IPR001634 Adenosine receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

3 interactions