Entity Details

Primary name SKI_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60698
EntryNameSKI_MOUSE
FullNameSki oncogene
TaxID10090
Evidenceevidence at protein level
Length725
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001843 neural tube closure
GO:0002089 lens morphogenesis in camera-type eye
GO:0003682 chromatin binding
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006351 transcription, DNA-templated
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0009948 anterior/posterior axis specification
GO:0010626 negative regulation of Schwann cell proliferation
GO:0014902 myotube differentiation
GO:0016604 nuclear body
GO:0016605 PML body
GO:0017053 transcription repressor complex
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0021772 olfactory bulb development
GO:0022011 myelination in peripheral nervous system
GO:0030326 embryonic limb morphogenesis
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0031625 ubiquitin protein ligase binding
GO:0032926 negative regulation of activin receptor signaling pathway
GO:0032991 protein-containing complex
GO:0035019 somatic stem cell population maintenance
GO:0042802 identical protein binding
GO:0043010 camera-type eye development
GO:0043388 positive regulation of DNA binding
GO:0043585 nose morphogenesis
GO:0045668 negative regulation of osteoblast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0046811 histone deacetylase inhibitor activity
GO:0048147 negative regulation of fibroblast proliferation
GO:0048593 camera-type eye morphogenesis
GO:0048741 skeletal muscle fiber development
GO:0060021 roof of mouth development
GO:0060041 retina development in camera-type eye
GO:0060325 face morphogenesis
GO:0060349 bone morphogenesis
GO:0060395 SMAD protein signal transduction
GO:0070208 protein heterotrimerization

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003380 SKI/SNO/DAC domainDomainDomain
IPR009061 Putative DNA-binding domain superfamilyFamilyHomologous superfamily
IPR010919 SAND-like domain superfamilyFamilyHomologous superfamily
IPR014890 c-SKI SMAD4-binding domainDomainDomain
IPR023216 Transcription regulator SKI/SnoNFamilyFamily
IPR028760 Ski oncogeneFamilyFamily
IPR037000 Ski-like, DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SKI_MOUSESATB2_MOUSEDIP22334647 details
SKI_MOUSESMAD4_MOUSEDIP29072299 details