Entity Details

Primary name SAMH1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60710
EntryNameSAMH1_MOUSE
FullNameDeoxynucleoside triphosphate triphosphohydrolase SAMHD1
TaxID10090
Evidenceevidence at protein level
Length658
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSamhd1

GO terms

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GOName
GO:0000724 double-strand break repair via homologous recombination
GO:0003676 nucleic acid binding
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0004540 ribonuclease activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0006203 dGTP catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008270 zinc ion binding
GO:0008832 dGTPase activity
GO:0009264 deoxyribonucleotide catabolic process
GO:0016446 somatic hypermutation of immunoglobulin genes
GO:0016793 triphosphoric monoester hydrolase activity
GO:0032567 dGTP binding
GO:0035861 site of double-strand break
GO:0042802 identical protein binding
GO:0045087 innate immune response
GO:0045088 regulation of innate immune response
GO:0046061 dATP catabolic process
GO:0051289 protein homotetramerization
GO:0051607 defense response to virus
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0097197 tetraspanin-enriched microdomain
GO:0110025 DNA strand resection involved in replication fork processing

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001660 Sterile alpha motif domainDomainDomain
IPR003607 HD/PDEase domainDomainDomain
IPR006674 HD domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions