Entity Details

Primary name ATF3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60765
EntryNameATF3_MOUSE
FullNameCyclic AMP-dependent transcription factor ATF-3
TaxID10090
Evidenceevidence at transcript level
Length181
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesAtf3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006094 gluconeogenesis
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0034198 cellular response to amino acid starvation
GO:0035914 skeletal muscle cell differentiation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway
GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:1990622 CHOP-ATF3 complex
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000837 AP-1 transcription factorFamilyFamily
IPR004827 Basic-leucine zipper domainDomainDomain
IPR029812 cAMP-dependent transcription factor ATF-3FamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ATF3_MOUSEJUN_MOUSEBioGRID, IntAct20211142 21304988 details
ATF3_MOUSEHSF1_MOUSEBioGRID17766920 details
ATF3_MOUSEHDAC2_MOUSEBioGRID22989952 details