Entity Details

Primary name TNAP3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60769
EntryNameTNAP3_MOUSE
FullNameTumor necrosis factor alpha-induced protein 3
TaxID10090
Evidenceevidence at protein level
Length775
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesTnfaip3

GO terms

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GOName
GO:0001922 B-1 B cell homeostasis
GO:0002020 protease binding
GO:0002237 response to molecule of bacterial origin
GO:0002315 marginal zone B cell differentiation
GO:0002632 negative regulation of granuloma formation
GO:0002634 regulation of germinal center formation
GO:0002637 regulation of immunoglobulin production
GO:0002677 negative regulation of chronic inflammatory response
GO:0003677 DNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007010 cytoskeleton organization
GO:0008022 protein C-terminus binding
GO:0008270 zinc ion binding
GO:0009611 response to wounding
GO:0010507 negative regulation of autophagy
GO:0016477 cell migration
GO:0016579 protein deubiquitination
GO:0019900 kinase binding
GO:0030177 positive regulation of Wnt signaling pathway
GO:0031397 negative regulation of protein ubiquitination
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032495 response to muramyl dipeptide
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032703 negative regulation of interleukin-2 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway
GO:0035523 protein K29-linked deubiquitination
GO:0035871 protein K11-linked deubiquitination
GO:0042802 identical protein binding
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ubiquitin binding
GO:0043621 protein self-association
GO:0045088 regulation of innate immune response
GO:0045732 positive regulation of protein catabolic process
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045824 negative regulation of innate immune response
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050728 negative regulation of inflammatory response
GO:0050869 negative regulation of B cell activation
GO:0060548 negative regulation of cell death
GO:0061578 Lys63-specific deubiquitinase activity
GO:0070301 cellular response to hydrogen peroxide
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding
GO:0070536 protein K63-linked deubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0071108 protein K48-linked deubiquitination
GO:0071222 cellular response to lipopolysaccharide
GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0072573 tolerance induction to lipopolysaccharide
GO:0072666 establishment of protein localization to vacuole
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1903364 positive regulation of cellular protein catabolic process
GO:1990168 protein K33-linked deubiquitination
GO:2000347 positive regulation of hepatocyte proliferation
GO:2000349 negative regulation of CD40 signaling pathway
GO:2000352 negative regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Lysosome
Nucleus

Domains

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DomainNameCategoryType
IPR002653 Zinc finger, A20-typeDomainDomain
IPR003323 OTU domainDomainDomain
IPR033478 A20 peptidaseFamilyFamily

Diseases

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