Entity Details

Primary name KLF4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60793
EntryNameKLF4_MOUSE
FullNameKrueppel-like factor 4
TaxID10090
Evidenceevidence at protein level
Length483
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesKlf4

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001010 RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity
GO:0001221 transcription coregulator binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002357 defense response to tumor cell
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0009913 epidermal cell differentiation
GO:0010033 response to organic substance
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling
GO:0014740 negative regulation of muscle hyperplasia
GO:0016525 negative regulation of angiogenesis
GO:0019827 stem cell population maintenance
GO:0030154 cell differentiation
GO:0030336 negative regulation of cell migration
GO:0031077 post-embryonic camera-type eye development
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032526 response to retinoic acid
GO:0032717 negative regulation of interleukin-8 production
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0035014 phosphatidylinositol 3-kinase regulator activity
GO:0035166 post-embryonic hemopoiesis
GO:0042127 regulation of cell population proliferation
GO:0042826 histone deacetylase binding
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045444 fat cell differentiation
GO:0045595 regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0046985 positive regulation of hemoglobin biosynthetic process
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0048679 regulation of axon regeneration
GO:0048730 epidermis morphogenesis
GO:0051247 positive regulation of protein metabolic process
GO:0051898 negative regulation of protein kinase B signaling
GO:0051973 positive regulation of telomerase activity
GO:0060070 canonical Wnt signaling pathway
GO:0060761 negative regulation of response to cytokine stimulus
GO:0070301 cellular response to hydrogen peroxide
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071300 cellular response to retinoic acid
GO:0071363 cellular response to growth factor stimulus
GO:0071409 cellular response to cycloheximide
GO:0071499 cellular response to laminar fluid shear stress
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis
GO:0120222 regulation of blastocyst development
GO:1901653 cellular response to peptide
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1903672 positive regulation of sprouting angiogenesis
GO:1904798 positive regulation of core promoter binding
GO:1904998 negative regulation of leukocyte adhesion to arterial endothelial cell
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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