Entity Details

Primary name PTPRO_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionE9Q612
EntryNamePTPRO_MOUSE
FullNameReceptor-type tyrosine-protein phosphatase O
TaxID10090
Evidenceevidence at protein level
Length1226
SequenceStatuscomplete
DateCreated2011-12-14
DateModified2021-06-02

Ontological Relatives

GenesPtpro

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0002548 monocyte chemotaxis
GO:0003093 regulation of glomerular filtration
GO:0003105 negative regulation of glomerular filtration
GO:0004725 protein tyrosine phosphatase activity
GO:0005886 plasma membrane
GO:0007411 axon guidance
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0017147 Wnt-protein binding
GO:0030032 lamellipodium assembly
GO:0032835 glomerulus development
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0036060 slit diaphragm assembly
GO:0042803 protein homodimerization activity
GO:0043197 dendritic spine
GO:0045296 cadherin binding
GO:0050807 regulation of synapse organization
GO:0072112 glomerular visceral epithelial cell differentiation
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099061 integral component of postsynaptic density membrane
GO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR042996 Receptor-type tyrosine-protein phosphatase OFamilyFamily

Diseases

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Interactions

3 interactions