Entity Details

Primary name PML_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60953
EntryNamePML_MOUSE
FullNameProtein PML
TaxID10090
Evidenceevidence at protein level
Length885
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPml

GO terms

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GOName
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0001666 response to hypoxia
GO:0001932 regulation of protein phosphorylation
GO:0002230 positive regulation of defense response to virus by host
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006605 protein targeting
GO:0006606 protein import into nucleus
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007182 common-partner SMAD protein phosphorylation
GO:0007569 cell aging
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411 response to UV
GO:0010332 response to gamma radiation
GO:0010522 regulation of calcium ion transport into cytosol
GO:0010761 fibroblast migration
GO:0016032 viral process
GO:0016363 nuclear matrix
GO:0016525 negative regulation of angiogenesis
GO:0016605 PML body
GO:0030099 myeloid cell differentiation
GO:0030155 regulation of cell adhesion
GO:0030308 negative regulation of cell growth
GO:0030578 PML body organization
GO:0031065 positive regulation of histone deacetylation
GO:0031625 ubiquitin protein ligase binding
GO:0031901 early endosome membrane
GO:0031965 nuclear membrane
GO:0032183 SUMO binding
GO:0032206 positive regulation of telomere maintenance
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032469 endoplasmic reticulum calcium ion homeostasis
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032692 negative regulation of interleukin-1 production
GO:0032922 circadian regulation of gene expression
GO:0032938 negative regulation of translation in response to oxidative stress
GO:0034097 response to cytokine
GO:0042406 extrinsic component of endoplasmic reticulum membrane
GO:0042752 regulation of circadian rhythm
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043153 entrainment of circadian clock by photoperiod
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087 innate immune response
GO:0045165 cell fate commitment
GO:0045343 regulation of MHC class I biosynthetic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045930 negative regulation of mitotic cell cycle
GO:0046332 SMAD binding
GO:0046982 protein heterodimerization activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0048384 retinoic acid receptor signaling pathway
GO:0050821 protein stabilization
GO:0050897 cobalt ion binding
GO:0051457 maintenance of protein location in nucleus
GO:0051607 defense response to virus
GO:0051974 negative regulation of telomerase activity
GO:0060058 positive regulation of apoptotic process involved in mammary gland involution
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0065003 protein-containing complex assembly
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071353 cellular response to interleukin-4
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090398 cellular senescence
GO:0097191 extrinsic apoptotic signaling pathway
GO:0140037 sumo-dependent protein binding
GO:1902187 negative regulation of viral release from host cell
GO:1904816 positive regulation of protein localization to chromosome, telomeric region
GO:1990830 cellular response to leukemia inhibitory factor
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
GO:2000779 regulation of double-strand break repair
GO:2001235 positive regulation of apoptotic signaling pathway
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome membrane
Endoplasmic reticulum membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000315 B-box-type zinc fingerDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR021978 Protein of unknown function DUF3583FamilyFamily

Diseases

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