Entity Details

Primary name NCOR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ60974
EntryNameNCOR1_MOUSE
FullNameNuclear receptor corepressor 1
TaxID10090
Evidenceevidence at protein level
Length2453
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0002155 regulation of thyroid hormone mediated signaling pathway
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0010629 negative regulation of gene expression
GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling
GO:0017053 transcription repressor complex
GO:0019904 protein domain specific binding
GO:0021794 thalamus development
GO:0030331 estrogen receptor binding
GO:0031065 positive regulation of histone deacetylation
GO:0032922 circadian regulation of gene expression
GO:0035033 histone deacetylase regulator activity
GO:0040014 regulation of multicellular organism growth
GO:0042632 cholesterol homeostasis
GO:0042826 histone deacetylase binding
GO:0042974 retinoic acid receptor binding
GO:0042975 peroxisome proliferator activated receptor binding
GO:0043565 sequence-specific DNA binding
GO:0045475 locomotor rhythm
GO:0045820 negative regulation of glycolytic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045922 negative regulation of fatty acid metabolic process
GO:0046329 negative regulation of JNK cascade
GO:0046965 retinoid X receptor binding
GO:0046966 thyroid hormone receptor binding
GO:0048471 perinuclear region of cytoplasm
GO:0051225 spindle assembly
GO:0060318 definitive erythrocyte differentiation
GO:0060766 negative regulation of androgen receptor signaling pathway
GO:0072686 mitotic spindle
GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA
GO:1904017 cellular response to Thyroglobulin triiodothyronine

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001005 SANT/Myb domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017884 SANT domainDomainDomain
IPR031557 N-CoR, GPS2-interacting domainDomainDomain

Diseases

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