Entity Details

Primary name NCOA2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61026
EntryNameNCOA2_MOUSE
FullNameNuclear receptor coactivator 2
TaxID10090
Evidenceevidence at protein level
Length1462
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesNcoa2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005874 microtubule
GO:0006355 regulation of transcription, DNA-templated
GO:0007623 circadian rhythm
GO:0008134 transcription factor binding
GO:0010468 regulation of gene expression
GO:0010906 regulation of glucose metabolic process
GO:0014069 postsynaptic density
GO:0016604 nuclear body
GO:0016922 nuclear receptor binding
GO:0017162 aryl hydrocarbon receptor binding
GO:0019904 protein domain specific binding
GO:0030165 PDZ domain binding
GO:0030331 estrogen receptor binding
GO:0030374 nuclear receptor coactivator activity
GO:0030425 dendrite
GO:0032570 response to progesterone
GO:0032870 cellular response to hormone stimulus
GO:0032922 circadian regulation of gene expression
GO:0032991 protein-containing complex
GO:0033142 progesterone receptor binding
GO:0035259 glucocorticoid receptor binding
GO:0042974 retinoic acid receptor binding
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0044877 protein-containing complex binding
GO:0045475 locomotor rhythm
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045925 positive regulation of female receptivity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046965 retinoid X receptor binding
GO:0046966 thyroid hormone receptor binding
GO:0046983 protein dimerization activity
GO:0048786 presynaptic active zone
GO:0070182 DNA polymerase binding
GO:1904017 cellular response to Thyroglobulin triiodothyronine
GO:2000324 positive regulation of glucocorticoid receptor signaling pathway

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR009110 Nuclear receptor coactivator, interlockingFamilyHomologous superfamily
IPR010011 Nuclear receptor coactivator, DUF1518DomainDomain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR013767 PAS foldDomainDomain
IPR014920 Nuclear receptor coactivator, Ncoa-type, interlockingDomainDomain
IPR014935 Nuclear receptor coactivator, receptor-binding domainDomainDomain
IPR017426 Nuclear receptor coactivatorFamilyFamily
IPR028822 Nuclear receptor coactivator 2FamilyFamily
IPR032565 Domain of unknown function DUF4927DomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037077 Nuclear receptor coactivator, Ncoa-type, interlocking domain superfamilyFamilyHomologous superfamily

Diseases

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