Entity Details

Primary name FZD6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61089
EntryNameFZD6_MOUSE
FullNameFrizzled-6
TaxID10090
Evidenceevidence at protein level
Length709
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFzd6

GO terms

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GOName
GO:0001736 establishment of planar polarity
GO:0001843 neural tube closure
GO:0001942 hair follicle development
GO:0004930 G protein-coupled receptor activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016327 apicolateral plasma membrane
GO:0017147 Wnt-protein binding
GO:0030168 platelet activation
GO:0030659 cytoplasmic vesicle membrane
GO:0030901 midbrain development
GO:0031625 ubiquitin protein ligase binding
GO:0033278 cell proliferation in midbrain
GO:0035567 non-canonical Wnt signaling pathway
GO:0035880 embryonic nail plate morphogenesis
GO:0042472 inner ear morphogenesis
GO:0042813 Wnt-activated receptor activity
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045177 apical part of cell
GO:0048105 establishment of body hair planar orientation
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Cell surface
Cytoplasmic vesicle membrane
Endoplasmic reticulum membrane
Membrane

Domains

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DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR026543 Frizzled-6FamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR041770 Frizzled 6, cysteine-rich domainDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink