Entity Details

Primary name FZD7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61090
EntryNameFZD7_MOUSE
FullNameFrizzled-7
TaxID10090
Evidenceevidence at protein level
Length572
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFzd7

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0005109 frizzled binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0010812 negative regulation of cell-substrate adhesion
GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
GO:0016021 integral component of membrane
GO:0017147 Wnt-protein binding
GO:0019827 stem cell population maintenance
GO:0030165 PDZ domain binding
GO:0033077 T cell differentiation in thymus
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035567 non-canonical Wnt signaling pathway
GO:0038031 non-canonical Wnt signaling pathway via JNK cascade
GO:0042327 positive regulation of phosphorylation
GO:0042666 negative regulation of ectodermal cell fate specification
GO:0042813 Wnt-activated receptor activity
GO:0043231 intracellular membrane-bounded organelle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048103 somatic stem cell division
GO:0055038 recycling endosome membrane
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0060070 canonical Wnt signaling pathway
GO:0060231 mesenchymal to epithelial transition
GO:0060828 regulation of canonical Wnt signaling pathway
GO:2000726 negative regulation of cardiac muscle cell differentiation

Subcellular Location

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Subcellular Location
Cell membrane
Endosome membrane

Domains

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DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR026552 Frizzled-7FamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR042742 Frizzled-7, cysteine-rich Wnt-binding domainDomainDomain

Diseases

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