Entity Details

Primary name FADD_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61160
EntryNameFADD_MOUSE
FullNameFAS-associated death domain protein
TaxID10090
Evidenceevidence at protein level
Length205
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesFadd

GO terms

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GOName
GO:0001822 kidney development
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002020 protease binding
GO:0002821 positive regulation of adaptive immune response
GO:0005123 death receptor binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0030217 T cell differentiation
GO:0031264 death-inducing signaling complex
GO:0031265 CD95 death-inducing signaling complex
GO:0032729 positive regulation of interferon-gamma production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032813 tumor necrosis factor receptor superfamily binding
GO:0032991 protein-containing complex
GO:0033077 T cell differentiation in thymus
GO:0033612 receptor serine/threonine kinase binding
GO:0035877 death effector domain binding
GO:0036462 TRAIL-activated apoptotic signaling pathway
GO:0042104 positive regulation of activated T cell proliferation
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043278 response to morphine
GO:0044297 cell body
GO:0044877 protein-containing complex binding
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0045651 positive regulation of macrophage differentiation
GO:0045862 positive regulation of proteolysis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048148 behavioral response to cocaine
GO:0048535 lymph node development
GO:0048536 spleen development
GO:0048538 thymus development
GO:0048738 cardiac muscle tissue development
GO:0051607 defense response to virus
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
GO:0060544 regulation of necroptotic process
GO:0060546 negative regulation of necroptotic process
GO:0070236 negative regulation of activation-induced cell death of T cells
GO:0071260 cellular response to mechanical stimulus
GO:0089720 caspase binding
GO:0097049 motor neuron apoptotic process
GO:0097190 apoptotic signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097202 activation of cysteine-type endopeptidase activity
GO:0097342 ripoptosome
GO:0097527 necroptotic signaling pathway
GO:2000454 positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR001875 Death effector domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR016729 FADDFamilyFamily

Diseases

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