Entity Details

Primary name PRDX2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61171
EntryNamePRDX2_MOUSE
FullNamePeroxiredoxin-2
TaxID10090
Evidenceevidence at protein level
Length198
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPrdx2

GO terms

Show/Hide Table
GOName
GO:0000187 obsolete activation of MAPK activity
GO:0002357 defense response to tumor cell
GO:0002536 respiratory burst involved in inflammatory response
GO:0004601 peroxidase activity
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006979 response to oxidative stress
GO:0008379 thioredoxin peroxidase activity
GO:0008430 selenium binding
GO:0010310 regulation of hydrogen peroxide metabolic process
GO:0016209 antioxidant activity
GO:0019430 removal of superoxide radicals
GO:0030194 positive regulation of blood coagulation
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032496 response to lipopolysaccharide
GO:0034599 cellular response to oxidative stress
GO:0042098 T cell proliferation
GO:0042743 hydrogen peroxide metabolic process
GO:0042744 hydrogen peroxide catabolic process
GO:0042981 regulation of apoptotic process
GO:0043209 myelin sheath
GO:0043524 negative regulation of neuron apoptotic process
GO:0045321 leukocyte activation
GO:0045454 cell redox homeostasis
GO:0045581 negative regulation of T cell differentiation
GO:0048538 thymus development
GO:0048872 homeostasis of number of cells
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidantDomainDomain
IPR013766 Thioredoxin domainDomainDomain
IPR019479 Peroxiredoxin, C-terminalDomainDomain
IPR024706 Peroxiredoxin, AhpC-typeFamilyFamily
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PRDX2_MOUSEHCD2_HUMANBioGRID22496890 details
PRDX2_MOUSEDPYL2_MOUSEBioGRID30315937 details