Entity Details

Primary name TS101_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61187
EntryNameTS101_MOUSE
FullNameTumor susceptibility gene 101 protein
TaxID10090
Evidenceevidence at protein level
Length391
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesTsg101

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000813 ESCRT I complex
GO:0001558 regulation of cell growth
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006513 protein monoubiquitination
GO:0006858 extracellular transport
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
GO:0008285 negative regulation of cell population proliferation
GO:0008333 endosome to lysosome transport
GO:0010008 endosome membrane
GO:0015031 protein transport
GO:0030154 cell differentiation
GO:0030216 keratinocyte differentiation
GO:0030374 nuclear receptor coactivator activity
GO:0031625 ubiquitin protein ligase binding
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043405 regulation of MAP kinase activity
GO:0044877 protein-containing complex binding
GO:0046755 viral budding
GO:0046790 virion binding
GO:0048306 calcium-dependent protein binding
GO:0051301 cell division
GO:0070062 extracellular exosome
GO:0090543 Flemming body
GO:1902188 positive regulation of viral release from host cell
GO:1903543 positive regulation of exosomal secretion
GO:1903551 regulation of extracellular exosome assembly
GO:1903774 positive regulation of viral budding via host ESCRT complex
GO:1990182 exosomal secretion
GO:2000397 positive regulation of ubiquitin-dependent endocytosis

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome membrane
Late endosome membrane
Midbody
Nucleus

Domains

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DomainNameCategoryType
IPR008883 Ubiquitin E2 variant, N-terminalDomainDomain
IPR016135 Ubiquitin-conjugating enzyme/RWD-likeFamilyHomologous superfamily
IPR017916 Steadiness box (SB) domainDomainDomain
IPR037202 ESCRT assembly domainFamilyHomologous superfamily

Diseases

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