Entity Details

Primary name SAP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61207
EntryNameSAP_MOUSE
FullNameProsaposin
TaxID10090
Evidenceevidence at protein level
Length557
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesPsap

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0001865 NK T cell differentiation
GO:0002020 protease binding
GO:0003335 corneocyte development
GO:0004565 beta-galactosidase activity
GO:0005543 phospholipid binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005770 late endosome
GO:0006643 membrane lipid metabolic process
GO:0006664 glycolipid metabolic process
GO:0006665 sphingolipid metabolic process
GO:0006672 ceramide metabolic process
GO:0006678 glucosylceramide metabolic process
GO:0006683 galactosylceramide catabolic process
GO:0006886 intracellular protein transport
GO:0007041 lysosomal transport
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007605 sensory perception of sound
GO:0009306 protein secretion
GO:0010467 gene expression
GO:0016235 aggresome
GO:0019216 regulation of lipid metabolic process
GO:0019882 antigen processing and presentation
GO:0021702 cerebellar Purkinje cell differentiation
GO:0030882 lipid antigen binding
GO:0032991 protein-containing complex
GO:0042552 myelination
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043408 regulation of MAPK cascade
GO:0043410 positive regulation of MAPK cascade
GO:0048589 developmental growth
GO:0050877 nervous system process
GO:0050885 neuromuscular process controlling balance
GO:0051345 positive regulation of hydrolase activity
GO:0060073 micturition
GO:0060736 prostate gland growth
GO:0060742 epithelial cell differentiation involved in prostate gland development
GO:0070841 inclusion body assembly
GO:0071310 cellular response to organic substance
GO:0090102 cochlea development
GO:0090659 walking behavior
GO:1903206 negative regulation of hydrogen peroxide-induced cell death
GO:1903575 cornified envelope assembly
GO:1905146 lysosomal protein catabolic process
GO:1905572 ganglioside GM1 transport to membrane
GO:1905573 ganglioside GM1 binding
GO:1905574 ganglioside GM2 binding
GO:1905575 ganglioside GM3 binding
GO:1905576 ganglioside GT1b binding
GO:1905577 ganglioside GP1c binding

Subcellular Location

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Subcellular Location
Lysosome
Secreted

Domains

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DomainNameCategoryType
IPR003119 Saposin A-type domainDomainDomain
IPR007856 Saposin-like type B, region 1DomainDomain
IPR008138 Saposin B type, region 2DomainDomain
IPR008139 Saposin B type domainDomainDomain
IPR008373 SaposinFamilyFamily
IPR011001 Saposin-likeFamilyHomologous superfamily
IPR021165 Saposin, chordataFamilyFamily

Diseases

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Interactions

6 interactions