Entity Details

Primary name SC6A3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61327
EntryNameSC6A3_MOUSE
FullNameSodium-dependent dopamine transporter
TaxID10090
Evidenceevidence at protein level
Length619
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSlc6a3

GO terms

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GOName
GO:0001504 neurotransmitter uptake
GO:0002020 protease binding
GO:0005102 signaling receptor binding
GO:0005326 neurotransmitter transmembrane transporter activity
GO:0005330 dopamine:sodium symporter activity
GO:0005334 norepinephrine:sodium symporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006836 neurotransmitter transport
GO:0007568 aging
GO:0007595 lactation
GO:0007608 sensory perception of smell
GO:0007626 locomotory behavior
GO:0008504 monoamine transmembrane transporter activity
GO:0009986 cell surface
GO:0010039 response to iron ion
GO:0015844 monoamine transport
GO:0015872 dopamine transport
GO:0015874 norepinephrine transport
GO:0016020 membrane
GO:0016600 flotillin complex
GO:0021984 adenohypophysis development
GO:0030424 axon
GO:0032809 neuronal cell body membrane
GO:0035094 response to nicotine
GO:0035240 dopamine binding
GO:0035725 sodium ion transmembrane transport
GO:0040018 positive regulation of multicellular organism growth
GO:0042053 regulation of dopamine metabolic process
GO:0042220 response to cocaine
GO:0042416 dopamine biosynthetic process
GO:0042420 dopamine catabolic process
GO:0042493 response to drug
GO:0042734 presynaptic membrane
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045471 response to ethanol
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
GO:0051583 dopamine uptake involved in synaptic transmission
GO:0051591 response to cAMP
GO:0051721 protein phosphatase 2A binding
GO:0060134 prepulse inhibition
GO:0090494 dopamine uptake
GO:0098691 dopaminergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:1990384 hyaloid vascular plexus regression

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000175 Sodium:neurotransmitter symporterFamilyFamily
IPR002436 Sodium:neurotransmitter symporter, dopamineFamilyFamily
IPR037272 Sodium:neurotransmitter symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01126 DutasterideDrugbanksmall molecule