Entity Details

Primary name TRAF4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61382
EntryNameTRAF4_MOUSE
FullNameTNF receptor-associated factor 4
TaxID10090
Evidenceevidence at protein level
Length470
SequenceStatuscomplete
DateCreated2003-05-09
DateModified2021-06-02

Ontological Relatives

GenesTraf4

GO terms

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GOName
GO:0001650 fibrillar center
GO:0005164 tumor necrosis factor receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005923 bicellular tight junction
GO:0006915 apoptotic process
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0030323 respiratory tube development
GO:0031625 ubiquitin protein ligase binding
GO:0031996 thioesterase binding
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045860 positive regulation of protein kinase activity
GO:0046330 positive regulation of JNK cascade
GO:0048471 perinuclear region of cytoplasm
GO:0050699 WW domain binding
GO:0070534 protein K63-linked ubiquitination

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001293 Zinc finger, TRAF-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR002083 MATH/TRAF domainDomainDomain
IPR008974 TRAF-likeFamilyHomologous superfamily
IPR012227 TNF receptor-associated factor TRAF, metazoaFamilyFamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR018957 Zinc finger, C3HC4 RING-typeDomainDomain
IPR027138 TNF receptor-associated factor 4FamilyFamily
IPR037307 TNF receptor-associated factor 4, MATH domainDomainDomain
IPR043211 TNF receptor-associated factor TRAFFamilyFamily

Diseases

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Interactions

4 interactions