Entity Details

Primary name HCDH_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61425
EntryNameHCDH_MOUSE
FullNameHydroxyacyl-coenzyme A dehydrogenase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length314
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesHadh

GO terms

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GOName
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0006635 fatty acid beta-oxidation
GO:0014823 response to activity
GO:0032868 response to insulin
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0046676 negative regulation of insulin secretion
GO:0050796 regulation of insulin secretion
GO:0070403 NAD+ binding
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminalDomainDomain
IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD bindingDomainDomain
IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved siteSiteConserved site
IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamilyFamilyHomologous superfamily
IPR013328 6-phosphogluconate dehydrogenase, domain 2FamilyHomologous superfamily
IPR022694 3-hydroxyacyl-CoA dehydrogenaseFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions