Entity Details

Primary name E2F1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61501
EntryNameE2F1_MOUSE
FullNameTranscription factor E2F1
TaxID10090
Evidenceevidence at protein level
Length430
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesE2f1

GO terms

Show/Hide Table
GOName
GO:0000077 DNA damage checkpoint signaling
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001216 DNA-binding transcription activator activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007283 spermatogenesis
GO:0008134 transcription factor binding
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010628 positive regulation of gene expression
GO:0019901 protein kinase binding
GO:0030900 forebrain development
GO:0032991 protein-containing complex
GO:0035189 Rb-E2F complex
GO:0043065 positive regulation of apoptotic process
GO:0043276 anoikis
GO:0043392 negative regulation of DNA binding
GO:0043565 sequence-specific DNA binding
GO:0045599 negative regulation of fat cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0048255 mRNA stabilization
GO:0051726 regulation of cell cycle
GO:0060252 positive regulation of glial cell proliferation
GO:0070345 negative regulation of fat cell proliferation
GO:0071398 cellular response to fatty acid
GO:0071456 cellular response to hypoxia
GO:0071466 cellular response to xenobiotic stimulus
GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090575 RNA polymerase II transcription regulator complex
GO:1990086 lens fiber cell apoptotic process
GO:1990090 cellular response to nerve growth factor stimulus
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR003316 E2F/DP family, winged-helix DNA-binding domainDomainDomain
IPR015633 E2F FamilyFamilyFamily
IPR032198 E2F transcription factor, CC-MB domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037241 E2F-DP heterodimerization regionFamilyHomologous superfamily

Diseases

Show/Hide Table