Entity Details

Primary name TRI25_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61510
EntryNameTRI25_MOUSE
FullNameE3 ubiquitin/ISG15 ligase TRIM25
TaxID10090
Evidenceevidence at protein level
Length634
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesTrim25

GO terms

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GOName
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006513 protein monoubiquitination
GO:0010494 cytoplasmic stress granule
GO:0016604 nuclear body
GO:0016874 ligase activity
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0032880 regulation of protein localization
GO:0033280 response to vitamin D
GO:0039552 RIG-I binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043627 response to estrogen
GO:0045087 innate immune response
GO:0046596 regulation of viral entry into host cell
GO:0046597 negative regulation of viral entry into host cell
GO:0046872 metal ion binding
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051607 defense response to virus
GO:0061630 ubiquitin protein ligase activity
GO:1902186 regulation of viral release from host cell
GO:1902187 negative regulation of viral release from host cell
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001870 B30.2/SPRY domainDomainDomain
IPR003877 SPRY domainDomainDomain
IPR003879 Butyrophylin-like, SPRY domainDomainDomain
IPR006574 SPRY-associatedDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR042753 TRIM25, PRY/SPRY domainDomainDomain
IPR043136 B30.2/SPRY domain superfamilyFamilyHomologous superfamily

Diseases

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