Entity Details

Primary name GDIR2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61599
EntryNameGDIR2_MOUSE
FullNameRho GDP-dissociation inhibitor 2
TaxID10090
Evidenceevidence at protein level
Length200
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesArhgdib

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005829 cytosol
GO:0007266 Rho protein signal transduction
GO:0016020 membrane
GO:0031267 small GTPase binding
GO:0035023 regulation of Rho protein signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0071461 cellular response to redox state
GO:1901164 negative regulation of trophoblast cell migration
GO:2000249 regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000406 Rho protein GDP-dissociation inhibitorFamilyFamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR024792 Rho GDP-dissociation inhibitor domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GDIR2_MOUSERAC3_MOUSEIntAct15102471 details
GDIR2_MOUSERN128_HUMANBioGRID17114425 details