Entity Details

Primary name DRD1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61616
EntryNameDRD1_MOUSE
FullNameD(1A) dopamine receptor
TaxID10090
Evidenceevidence at protein level
Length446
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDrd1

GO terms

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GOName
GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs
GO:0001659 temperature homeostasis
GO:0001661 conditioned taste aversion
GO:0001662 behavioral fear response
GO:0001932 regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0001963 synaptic transmission, dopaminergic
GO:0001965 G-protein alpha-subunit binding
GO:0001975 response to amphetamine
GO:0004930 G protein-coupled receptor activity
GO:0004952 dopamine neurotransmitter receptor activity
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0005929 cilium
GO:0006469 negative regulation of protein kinase activity
GO:0006606 protein import into nucleus
GO:0006886 intracellular protein transport
GO:0006936 muscle contraction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007212 dopamine receptor signaling pathway
GO:0007612 learning
GO:0007613 memory
GO:0007617 mating behavior
GO:0007625 grooming behavior
GO:0007626 locomotory behavior
GO:0007628 adult walking behavior
GO:0007631 feeding behavior
GO:0008306 associative learning
GO:0008542 visual learning
GO:0010628 positive regulation of gene expression
GO:0012505 endomembrane system
GO:0014002 astrocyte development
GO:0015872 dopamine transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019226 transmission of nerve impulse
GO:0019228 neuronal action potential
GO:0019229 regulation of vasoconstriction
GO:0019722 calcium-mediated signaling
GO:0019903 protein phosphatase binding
GO:0021542 dentate gyrus development
GO:0021756 striatum development
GO:0021766 hippocampus development
GO:0021853 cerebral cortex GABAergic interneuron migration
GO:0030335 positive regulation of cell migration
GO:0030336 negative regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030432 peristalsis
GO:0031701 angiotensin receptor binding
GO:0031750 D3 dopamine receptor binding
GO:0035106 operant conditioning
GO:0035176 social behavior
GO:0035240 dopamine binding
GO:0042053 regulation of dopamine metabolic process
GO:0042220 response to cocaine
GO:0042311 vasodilation
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep
GO:0042493 response to drug
GO:0042711 maternal behavior
GO:0042755 eating behavior
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
GO:0043269 regulation of ion transport
GO:0043679 axon terminus
GO:0043987 histone H3-S10 phosphorylation
GO:0044326 dendritic spine neck
GO:0044327 dendritic spine head
GO:0044877 protein-containing complex binding
GO:0045838 positive regulation of membrane potential
GO:0046323 glucose import
GO:0046959 habituation
GO:0046960 sensitization
GO:0048148 behavioral response to cocaine
GO:0050805 negative regulation of synaptic transmission
GO:0051117 ATPase binding
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060158 phospholipase C-activating dopamine receptor signaling pathway
GO:0060170 ciliary membrane
GO:0060291 long-term synaptic potentiation
GO:0060292 long-term synaptic depression
GO:0060548 negative regulation of cell death
GO:0071870 cellular response to catecholamine stimulus
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0097730 non-motile cilium
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099010 modification of postsynaptic structure
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:0099170 postsynaptic modulation of chemical synaptic transmission
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1903351 cellular response to dopamine
GO:2000253 positive regulation of feeding behavior
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000929 Dopamine receptor familyFamilyFamily
IPR001413 Dopamine D1 receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DRD1_MOUSEPE2R1_MOUSEBioGRID23842570 details
DRD1_MOUSEPDC6I_MOUSEBioGRID18380665 details