Entity Details

Primary name DDX5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61656
EntryNameDDX5_MOUSE
FullNameProbable ATP-dependent RNA helicase DDX5
TaxID10090
Evidenceevidence at protein level
Length614
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0001837 epithelial to mesenchymal transition
GO:0003712 transcription coregulator activity
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0003730 mRNA 3'-UTR binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006606 protein import into nucleus
GO:0007623 circadian rhythm
GO:0009299 mRNA transcription
GO:0019899 enzyme binding
GO:0030509 BMP signaling pathway
GO:0030520 intracellular estrogen receptor signaling pathway
GO:0030521 androgen receptor signaling pathway
GO:0035500 MH2 domain binding
GO:0036002 pre-mRNA binding
GO:0043021 ribonucleoprotein complex binding
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045069 regulation of viral genome replication
GO:0045445 myoblast differentiation
GO:0045667 regulation of osteoblast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046332 SMAD binding
GO:0048306 calcium-dependent protein binding
GO:0050681 androgen receptor binding
GO:0060765 regulation of androgen receptor signaling pathway
GO:0061614 pri-miRNA transcription by RNA polymerase II
GO:0070412 R-SMAD binding
GO:0070878 primary miRNA binding
GO:0071013 catalytic step 2 spliceosome
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA
GO:1990841 promoter-specific chromatin binding
GO:1990904 ribonucleoprotein complex
GO:2001014 regulation of skeletal muscle cell differentiation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000629 ATP-dependent RNA helicase DEAD-box, conserved siteSiteConserved site
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR012587 RNA helicase p68 repeatRepeatRepeat
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014014 RNA helicase, DEAD-box type, Q motifDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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