Entity Details

Primary name ATRX_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61687
EntryNameATRX_MOUSE
FullNameTranscriptional regulator ATRX
TaxID10090
Evidenceevidence at protein level
Length2476
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesAtrx

GO terms

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GOName
GO:0000212 meiotic spindle organization
GO:0000228 nuclear chromosome
GO:0000779 condensed chromosome, centromeric region
GO:0000781 chromosome, telomeric region
GO:0000792 heterochromatin
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005721 pericentric heterochromatin
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006334 nucleosome assembly
GO:0006336 DNA replication-independent nucleosome assembly
GO:0006338 chromatin remodeling
GO:0007283 spermatogenesis
GO:0010571 positive regulation of nuclear cell cycle DNA replication
GO:0015616 DNA translocase activity
GO:0016604 nuclear body
GO:0016605 PML body
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0030900 forebrain development
GO:0031297 replication fork processing
GO:0032206 positive regulation of telomere maintenance
GO:0035064 methylated histone binding
GO:0035128 post-embryonic forelimb morphogenesis
GO:0035264 multicellular organism growth
GO:0042393 histone binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0060009 Sertoli cell development
GO:0070087 chromo shadow domain binding
GO:0070192 chromosome organization involved in meiotic cell cycle
GO:0070198 protein localization to chromosome, telomeric region
GO:0070615 nucleosome-dependent ATPase activity
GO:0072520 seminiferous tubule development
GO:0072711 cellular response to hydroxyurea
GO:0099115 chromosome, subtelomeric region
GO:1900112 regulation of histone H3-K9 trimethylation
GO:1901581 negative regulation of telomeric RNA transcription from RNA pol II promoter
GO:1901582 positive regulation of telomeric RNA transcription from RNA pol II promoter
GO:1904908 negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR025766 ADD domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily
IPR041430 ATRX, ADD domainDomainDomain

Diseases

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