Entity Details

Primary name HS71A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61696
EntryNameHS71A_MOUSE
FullNameHeat shock 70 kDa protein 1A
TaxID10090
Evidenceevidence at protein level
Length641
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesHspa1a

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0001664 G protein-coupled receptor binding
GO:0002020 protease binding
GO:0003714 transcription corepressor activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006281 DNA repair
GO:0006402 mRNA catabolic process
GO:0006457 protein folding
GO:0006986 response to unfolded protein
GO:0007041 lysosomal transport
GO:0008285 negative regulation of cell population proliferation
GO:0009408 response to heat
GO:0016192 vesicle-mediated transport
GO:0016234 inclusion body
GO:0016235 aggresome
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016607 nuclear speck
GO:0016887 ATP hydrolysis activity
GO:0019899 enzyme binding
GO:0030308 negative regulation of cell growth
GO:0031072 heat shock protein binding
GO:0031249 denatured protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032991 protein-containing complex
GO:0034620 cellular response to unfolded protein
GO:0042026 protein refolding
GO:0042826 histone deacetylase binding
GO:0044183 protein folding chaperone
GO:0045121 membrane raft
GO:0047485 protein N-terminus binding
GO:0048471 perinuclear region of cytoplasm
GO:0051059 NF-kappaB binding
GO:0051082 unfolded protein binding
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0051787 misfolded protein binding
GO:0055131 C3HC4-type RING finger domain binding
GO:0090063 positive regulation of microtubule nucleation
GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress
GO:0097718 disordered domain specific binding
GO:1901673 regulation of mitotic spindle assembly
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR013126 Heat shock protein 70 familyFamilyFamily
IPR018181 Heat shock protein 70, conserved siteSiteConserved site
IPR029047 Heat shock protein 70kD, peptide-binding domain superfamilyFamilyHomologous superfamily
IPR029048 Heat shock protein 70kD, C-terminal domain superfamilyFamilyHomologous superfamily
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

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Interactions

3 interactions