Entity Details

Primary name ITA6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61739
EntryNameITA6_MOUSE
FullNameIntegrin alpha-6
TaxID10090
Evidenceevidence at protein level
Length1091
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesItga6

GO terms

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GOName
GO:0005178 integrin binding
GO:0005604 basement membrane
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009925 basal plasma membrane
GO:0009986 cell surface
GO:0010811 positive regulation of cell-substrate adhesion
GO:0010976 positive regulation of neuron projection development
GO:0016323 basolateral plasma membrane
GO:0022409 positive regulation of cell-cell adhesion
GO:0030056 hemidesmosome
GO:0030175 filopodium
GO:0030335 positive regulation of cell migration
GO:0031589 cell-substrate adhesion
GO:0031668 cellular response to extracellular stimulus
GO:0031994 insulin-like growth factor I binding
GO:0033627 cell adhesion mediated by integrin
GO:0034676 integrin alpha6-beta4 complex
GO:0035878 nail development
GO:0038132 neuregulin binding
GO:0042327 positive regulation of phosphorylation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043065 positive regulation of apoptotic process
GO:0043236 laminin binding
GO:0043547 positive regulation of GTPase activity
GO:0043589 skin morphogenesis
GO:0044877 protein-containing complex binding
GO:0045178 basal part of cell
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046847 filopodium assembly
GO:0046872 metal ion binding
GO:0050873 brown fat cell differentiation
GO:0050900 leukocyte migration
GO:0098609 cell-cell adhesion
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000413 Integrin alpha chainFamilyFamily
IPR013517 FG-GAP repeatRepeatRepeat
IPR013519 Integrin alpha beta-propellorRepeatRepeat
IPR013649 Integrin alpha-2DomainDomain
IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved siteSiteConserved site
IPR028994 Integrin alpha, N-terminalFamilyHomologous superfamily
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions