Entity Details

Primary name LTBP3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61810
EntryNameLTBP3_MOUSE
FullNameLatent-transforming growth factor beta-binding protein 3
TaxID10090
Evidenceevidence at protein level
Length1253
SequenceStatuscomplete
DateCreated2004-01-16
DateModified2021-06-02

Ontological Relatives

GenesLtbp3

GO terms

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GOName
GO:0001501 skeletal system development
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0030502 negative regulation of bone mineralization
GO:0031012 extracellular matrix
GO:0032331 negative regulation of chondrocyte differentiation
GO:0036363 transforming growth factor beta activation
GO:0045780 positive regulation of bone resorption
GO:0046849 bone remodeling
GO:0048251 elastic fiber assembly
GO:0050431 transforming growth factor beta binding
GO:0060349 bone morphogenesis
GO:0060430 lung saccule development
GO:0062023 collagen-containing extracellular matrix
GO:1902462 positive regulation of mesenchymal stem cell proliferation
GO:2000741 positive regulation of mesenchymal stem cell differentiation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR017878 TB domainDomainDomain
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR036773 TGF-beta binding (TB) domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
LTBP3_MOUSEDUX4_HUMANBioGRID, IntAct26816005 details
LTBP3_MOUSETGFB1_MOUSEBioGRID, DIP19022904 7730318 details