Entity Details

Primary name PDCD4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61823
EntryNamePDCD4_MOUSE
FullNameProgrammed cell death protein 4
TaxID10090
Evidenceevidence at protein level
Length469
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesPdcd4

GO terms

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GOName
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0007569 cell aging
GO:0030509 BMP signaling pathway
GO:0034393 positive regulation of smooth muscle cell apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043508 negative regulation of JUN kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050729 positive regulation of inflammatory response
GO:0051246 regulation of protein metabolic process
GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development
GO:0071222 cellular response to lipopolysaccharide
GO:1900016 negative regulation of cytokine production involved in inflammatory response
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1904761 negative regulation of myofibroblast differentiation
GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation
GO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process
GO:2000353 positive regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003891 Initiation factor eIF-4 gamma, MA3DomainDomain
IPR016021 MIF4G-like domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR039778 Programmed cell death protein 4FamilyFamily

Diseases

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Interactions

3 interactions