Entity Details

Primary name NF2L1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ61985
EntryNameNF2L1_MOUSE
FullNameEndoplasmic reticulum membrane sensor NFE2L1
TaxID10090
Evidenceevidence at protein level
Length741
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesNfe2l1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000209 protein polyubiquitination
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006002 fructose 6-phosphate metabolic process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006749 glutathione metabolic process
GO:0007088 regulation of mitotic nuclear division
GO:0008203 cholesterol metabolic process
GO:0010468 regulation of gene expression
GO:0010906 regulation of glucose metabolic process
GO:0015485 cholesterol binding
GO:0019216 regulation of lipid metabolic process
GO:0019217 regulation of fatty acid metabolic process
GO:0019725 cellular homeostasis
GO:0019904 protein domain specific binding
GO:0021522 spinal cord motor neuron differentiation
GO:0021781 glial cell fate commitment
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030218 erythrocyte differentiation
GO:0032991 protein-containing complex
GO:0034599 cellular response to oxidative stress
GO:0034976 response to endoplasmic reticulum stress
GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0042632 cholesterol homeostasis
GO:0042883 cysteine transport
GO:0044877 protein-containing complex binding
GO:0045454 cell redox homeostasis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0050727 regulation of inflammatory response
GO:0051156 glucose 6-phosphate metabolic process
GO:0055088 lipid homeostasis
GO:0061136 regulation of proteasomal protein catabolic process
GO:0070417 cellular response to cold
GO:0071280 cellular response to copper ion
GO:0071397 cellular response to cholesterol
GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress
GO:1901329 regulation of odontoblast differentiation
GO:1903353 regulation of nucleus organization
GO:1905897 regulation of response to endoplasmic reticulum stress
GO:1990841 promoter-specific chromatin binding

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Nucleus

Domains

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DomainNameCategoryType
IPR004826 Basic leucine zipper domain, Maf-typeDomainDomain
IPR004827 Basic-leucine zipper domainDomainDomain
IPR008917 Transcription factor, Skn-1-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR029847 Endoplasmic reticulum membrane sensor NFE2L1FamilyFamily

Diseases

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Interactions

0 interactions

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