Entity Details

Primary name KPCI_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ62074
EntryNameKPCI_MOUSE
FullNameProtein kinase C iota type
TaxID10090
Evidenceevidence at protein level
Length595
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesPrkci

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005524 ATP binding
GO:0005543 phospholipid binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005923 bicellular tight junction
GO:0006468 protein phosphorylation
GO:0007015 actin filament organization
GO:0010976 positive regulation of neuron projection development
GO:0015630 microtubule cytoskeleton
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0018105 peptidyl-serine phosphorylation
GO:0031252 cell leading edge
GO:0032869 cellular response to insulin stimulus
GO:0034351 negative regulation of glial cell apoptotic process
GO:0034613 cellular protein localization
GO:0035089 establishment of apical/basal cell polarity
GO:0035556 intracellular signal transduction
GO:0042462 eye photoreceptor cell development
GO:0043220 Schmidt-Lanterman incisure
GO:0043434 response to peptide hormone
GO:0043524 negative regulation of neuron apoptotic process
GO:0045171 intercellular bridge
GO:0045177 apical part of cell
GO:0045216 cell-cell junction organization
GO:0046326 positive regulation of glucose import
GO:0046872 metal ion binding
GO:0048194 Golgi vesicle budding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060252 positive regulation of glial cell proliferation
GO:0070555 response to interleukin-1
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903078 positive regulation of protein localization to plasma membrane
GO:2000353 positive regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Endosome
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000270 PB1 domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR012233 Protein kinase CFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain
IPR034661 Atypical protein kinase C iota type, catalytic domainDomainDomain
IPR034877 Protein kinase C, PB1 domainDomainDomain

Diseases

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