Entity Details

Primary name KPCD1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ62101
EntryNameKPCD1_MOUSE
FullNameSerine/threonine-protein kinase D1
TaxID10090
Evidenceevidence at protein level
Length918
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesPrkd1

GO terms

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GOName
GO:0000421 autophagosome membrane
GO:0001525 angiogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005938 cell cortex
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007030 Golgi organization
GO:0007265 Ras protein signal transduction
GO:0007399 nervous system development
GO:0010508 positive regulation of autophagy
GO:0010595 positive regulation of endothelial cell migration
GO:0010837 regulation of keratinocyte proliferation
GO:0010976 positive regulation of neuron projection development
GO:0016301 kinase activity
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030154 cell differentiation
GO:0031647 regulation of protein stability
GO:0032793 positive regulation of CREB transcription factor activity
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034198 cellular response to amino acid starvation
GO:0034599 cellular response to oxidative stress
GO:0035556 intracellular signal transduction
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0042307 positive regulation of protein import into nucleus
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045087 innate immune response
GO:0045669 positive regulation of osteoblast differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048193 Golgi vesicle transport
GO:0050829 defense response to Gram-negative bacterium
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051279 regulation of release of sequestered calcium ion into cytosol
GO:0060548 negative regulation of cell death
GO:0071447 cellular response to hydroperoxide
GO:0089700 protein kinase D signaling
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901727 positive regulation of histone deacetylase activity
GO:2001028 positive regulation of endothelial cell chemotaxis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015727 Protein kinase C mu-relatedFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain

Diseases

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Interactions

3 interactions