Entity Details

Primary name SOS1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ62245
EntryNameSOS1_MOUSE
FullNameSon of sevenless homolog 1
TaxID10090
Evidenceevidence at protein level
Length1319
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesSos1

GO terms

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GOName
GO:0001782 B cell homeostasis
GO:0001942 hair follicle development
GO:0002260 lymphocyte homeostasis
GO:0003007 heart morphogenesis
GO:0003209 cardiac atrium morphogenesis
GO:0003344 pericardium morphogenesis
GO:0003677 DNA binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0007265 Ras protein signal transduction
GO:0007296 vitellogenesis
GO:0014069 postsynaptic density
GO:0017124 SH3 domain binding
GO:0033081 regulation of T cell differentiation in thymus
GO:0035264 multicellular organism growth
GO:0042129 regulation of T cell proliferation
GO:0043025 neuronal cell body
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046982 protein heterodimerization activity
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048514 blood vessel morphogenesis
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0060021 roof of mouth development
GO:0061029 eyelid development in camera-type eye
GO:0061384 heart trabecula morphogenesis
GO:1904693 midbrain morphogenesis
GO:2000973 regulation of pro-B cell differentiation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR000651 Ras-like guanine nucleotide exchange factor, N-terminalDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR001895 Ras guanine-nucleotide exchange factors catalytic domainDomainDomain
IPR007125 Histone H2A/H2B/H3DomainDomain
IPR008937 Ras-like guanine nucleotide exchange factorFamilyFamily
IPR009072 Histone-foldFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR019804 Ras guanine-nucleotide exchange factor, conserved siteSiteConserved site
IPR023578 Ras guanine nucleotide exchange factor domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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