Entity Details

Primary name ZIC2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ62520
EntryNameZIC2_MOUSE
FullNameZinc finger protein ZIC 2
TaxID10090
Evidenceevidence at protein level
Length530
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001843 neural tube closure
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0007601 visual perception
GO:0016604 nuclear body
GO:0030154 cell differentiation
GO:0031290 retinal ganglion cell axon guidance
GO:0031490 chromatin DNA binding
GO:0044782 cilium organization
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048066 developmental pigmentation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily
IPR041643 ZIC protein, zinc finger domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ZIC2_MOUSEGLI1_HUMANMINT11238441 details
ZIC2_MOUSEGLI3_HUMANMINT11238441 details